CT supports therapy as effective in those with acute coronary syndrome
Coronary CT angiography proved the effectiveness of a therapy for patients who experience acute coronary syndrome (ACS), according to research published in JACC: Cardiovascular Imaging.
The study, published online Oct. 18, showed how low-dose colchicine therapy can favorably remodel coronary plaque, a prominent predictor of future cardiovascular events, after ACS.
“Our findings suggest, for the first time, that low-dose colchicine therapy favorably modifies coronary plaque, independent of high-dose statin intensification therapy and substantial low-density lipoprotein reduction,” wrote Kaivan Vaidya, MBBS, with the department of cardiology at Royal Prince Alfred Hospital in Sydney, and colleagues. “The improvements in plaque morphology are likely driven by the anti-inflammatory properties of colchicine, as demonstrated by reductions in hsCRP, rather than changes in lipoproteins. Colchicine may be beneficial as an additional secondary prevention agent in patients post-ACS if validated in future studies.”
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