Researchers have linked specific gene mutations and brain function in Huntington’s disease (HD) patients by comparing trinucleotide (CAG) repeats with whole-brain connectivity via functional MRI (fMRI). Examining disease carriers and health controls, the researchers found CAG repeat length inversely correlates with an individual’s age at onset.
Researchers have linked specific gene mutations and brain function in Huntington’s disease (HD) patients by comparing trinucleotide (CAG) repeats with whole-brain connectivity via functional MRI (fMRI). Examining disease carriers and health controls, the researchers found CAG repeat length inversely correlates with an individual’s age at onset.