BREMEN, Germany & BURLINGTON, Mass. — Background: Lung cancer is the number one cancer killer in the United States, causing more deaths each year than breast, colon, pancreas and prostate cancers combined. The National Lung Screening Trial proved that CT lung cancer screening (LCS) can reduce deaths due to lung cancer by at least 20% in individuals at high-risk. The resulting endorsement of LCS by the United States Preventive Services Task Force means that millions of high-risk Americans will be granted insurance coverage for annual LCS beginning in 2015.