Clinical Research

Oncology imaging AI growing fast yet still in its infancy

If generalizable AI models are to meaningfully contribute to precision cancer care, they’ll need to incorporate not only imaging data but also digitalized clinical notes, biomarker assays and monitor readouts.

Formidable tumors tamed by genetically modified … herpes?

A genetically engineered iteration of the herpes simplex virus has beaten back several advanced cancers in an early trial.

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Transplanted lungs react to COVID in a distinctive way

Clinicians treating COVID-19 patients who have transplanted lungs and lower airway infection should order molecular testing in addition to, or regardless of, imaging findings.

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New amyloid buster significantly hinders Alzheimer’s advance

An experimental Alzheimer’s drug therapy has slowed cognitive and functional decline by 27% versus placebo in a double-blind, randomized study of 1,795 individuals with early signs and symptoms of the disease.

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For monitoring purposes, AI-aided MRI does what liver biopsy does with less risk, lower cost

Patients with autoimmune hepatitis may be better monitored across disease stages by AI-augmented multiparametric MRI than by liver biopsy, as the imaging has proven less costly and is inherently less risky due to its noninvasiveness. 

RSNA to shutter print journals

Collectors of medical memorabilia may want to plan on preserving the January 2023 print edition of Radiology.

On review, popular imaging decision aid earns 1 thumbs-up—with caveats

With 91% sensitivity but only 25% specificity, the tool is worthwhile for clinicians who remain wary of frequent false positives that would send patients with no fractures for unneeded imaging.

Could a repurposed drug break a centurylong stalemate in the war on cancer?

A pharmaceutical compound approved 21 years ago to treat breast cancer in postmenopausal women is showing fresh promise as a therapy for glioblastomas. 

Around the web

The patient, who was being cared for in the ICU, was not accompanied or monitored by nursing staff during his exam, despite being sedated.

The nuclear imaging isotope shortage of molybdenum-99 may be over now that the sidelined reactor is restarting. ASNC's president says PET and new SPECT technologies helped cardiac imaging labs better weather the storm.

CMS has more than doubled the CCTA payment rate from $175 to $357.13. The move, expected to have a significant impact on the utilization of cardiac CT, received immediate praise from imaging specialists.