Clinical Research

Architectural distortion seen in the breast of a 67-year-old woman who presented for screening mammography. Surgical pathology revealed invasive ductal adenocarcinoma. Image from AJR

When does worrisome architectural distortion signal malignancy on mammography?

Architectural distortion, the non-mass but potentially ominous clinical feature observed in many breast imaging procedures, is less likely to signal malignancy when it’s detected on screening mammography rather than diagnostic mammography or when it does not correlate with a subsequent targeted ultrasound exam.

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