Nuclear Medicine

Nuclear medicine (also called molecular imaging) includes positron emission computed tomography (PET) and single photon emission computed tomography (SPECT) imaging. Nuclear imaging is achieved by injecting small amounts of radioactive material (radiopharmaceuticals) into patients before or during their scan. These can use sugars or chemical traits to bond to specific cells. The radioactive material is taken up by cells that consume the sugars. The radiation emitted from inside the body is detected by photon detectors outside the body. Computers take the data to assemble images of the radiation emissions. Nuclear images may appear fuzzy or ghostly rather than the sharper resolution from MRI and CT.  But, it provides metabolic information at a cellular level, showing if there are defects in the function of the heart, areas of very high metabolic activity associated with cancer cells, or areas of inflammation, data not available from other modalities. These noninvasive imaging exams are used to diagnose cancer, heart disease, Alzheimer’s and Parkinson’s disease, bone disorders and other disorders. 

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GE HealthCare recalling nuclear imaging systems as FDA warns of dangerous consequences

The FDA alerted patients and providers about the issue Feb. 15, labeling it as the agency’s “most serious” type of recall. 

FDA grants passage to autonomous, biology-guided radiotherapy

A therapeutic oncology company has been cleared to market a cancer treatment that that turns a tumor’s own biology into a self-signaling target for radiation therapy.

Mo-99 supplier reaches ‘major milestone’ in non-uranium-based production

Backed with financial support and technical prowess from the U.S. Department of Energy, NorthStar Medical Radioisotopes has shown it can produce, at scale, a critical nuclear imaging radiotracer without using highly enriched uranium.

ASNC 2023 president calls for nuclear cardiology to embrace new technology

American Society of Nuclear Cardiology (ASNC) 2023 President Mouaz H. Al-Mallah, MD, said the subspecialty needs to up its game with new technology.

A CT coronary calcium scoring exam at Northwestern Medicine's Central DuPage Hospital in the Chicago Suburbs. Dave Fornell

Trends in the number of radiology studies and a decline in radiation dose

A special report in Radiology offers a rare overview of the number of radiology exams performed each year worldwide and focuses on the decline of associated radiation doses patients receive.

FDA expands indications for neuroimaging radiotracer

An established radiopharmaceutical can now be applied with the FDA’s blessing when symptoms of cognitive decline point to the second most common form of degenerative dementia (after only Alzheimer’s disease).  

FAPI PET/CT shows promise as a better radiotracer for cancer than 18F-FDG. It also can be used for detection of infection and inflammation.

VIDEO: 6 key advances in molecular imaging technology for PET and SPECT

Munir Ghesani, MD, President of the Society of Nuclear Medicine and Molecular Imaging (SNMMI), system chief of nuclear medicine at Mount Sinai Health, explains recent advances in nuclear imaging technology.

Two examples of PSMA-PET scans showing numerous prostate cancer metastases spread throughout the body. Many of these smaller tumors would not have been dected on previous standard-of-care imaging. Photo on left courtesy of SNMMI, right University of Chicago. #PSMAPET

PSMA-PET is rapidly changing the standard of care for prostate cancer patients

Adoption of PSMA-PET has been swift because it can significantly improve prostate cancer detection and treatment. SNMMI President Munir Ghesani, MD, explains how.

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Around the web

Cardiovascular Business
Global shortage of nuclear imaging isotopes may be over

The nuclear imaging isotope shortage of molybdenum-99 may be over now that the sidelined reactor is restarting. ASNC's president says PET and new SPECT technologies helped cardiac imaging labs better weather the storm.

Cardiovascular Business
‘A huge win’: CMS significantly increases Medicare payments for cardiac CT

CMS has more than doubled the CCTA payment rate from $175 to $357.13. The move, expected to have a significant impact on the utilization of cardiac CT, received immediate praise from imaging specialists.

Cardiovascular Business
GE HealthCare moves PET/CT scanner production to United States

The all-in-one Omni Legend PET/CT scanner is now being manufactured in a new production facility in Waukesha, Wisconsin.